Humalog Mix 25 cartridge is a premixed suspension that is usually prescribed along with long-acting type insulin. It combines two medications used to manage blood sugar levels and severe complications related to type 1 and type 2 diabetes mellitus.

Humalog Mix 25 100IU/ml Cartridge has a prolonged duration of action and a fast onset of action. Together, it ensures rapid and consistent control to manage blood glucose levels throughout the day.

A doctor or nurse should provide training on how to administer insulin in the form of injection properly. Managing your blood sugar levels is an essential part of diabetes management which can help you avoid any risks and complications such as eye damage, kidney damage, nerve problems, or loss of limbs.

25% insulin lispro is the active substance dissolved in water. It works faster than insulin produced by the body since it has had a molecular modification. Protamine sulfate makes up the other 75% of Humalog Mix 25 in the form of a suspension.

Humalog has many products including, KwikPens 200, Mix 25 KwikPens, vials and cartridges. These products come in a wide array of mixes including Mix 50.

Your doctor or nurse will provide instruction on how to inject under the skin properly. It should be taken 15 minutes before starting your meal or within 20 minutes of creating your meal. Do not discontinue using insulin unless advised by your doctor.

Humalog Mix 25 should be used as part of a treatment program that includes a healthy diet, weight loss, and exercise program as advised by your doctor, allowing patients to live a more healthy life.

Warnings and Precautions

Hypoglycemia or low blood sugar is the most common adverse effect experienced by insulin users. Blood glucose monitoring is recommended for all patients with diabetes (type 1, type 2, gestational and brittle). Uncorrected hypoglycemic or hyperglycemic reactions can cause loss of consciousness, coma, or even death. Information on how to recognize these symptoms is provided below.

Humalog Mix25 should be given within 15 minutes before a meal.

Humalog Mix25 is a white suspension and should be administered by subcutaneous injection only. Humalog Mix25 must not be administered intravenously.

Any change of insulin regimen should be made cautiously and only under medical supervision. Changes in purity, strength, brand (manufacturer), type (regular, NPH, etc.), species (beef, pork, beef-pork, human), and method of manufacture (recombinant DNA versus animal-source insulin) may result in the need for a change in dosage.

Mixing Humalog Mix25 with either animal insulins or insulin preparations produced by other manufacturers is not recommended.

Patients taking Humalog Mix25 may require a change in dosage from that used with other insulins. If an adjustment is needed, it may occur with the first dose or over several weeks. It is easy for patients to get confused between Humalog and Humulin (as they have similar names). Please be sure you are using the appropriate insulin that your doctor has recommended.


It is essential to check your blood sugar levels regularly, keep track of your results and share them with your doctor so they can prescribe the correct dose for you.

Humalog Mix25 should be used 15 minutes before starting a meal and within 20 minutes of creating your meal.

Inject insulin as instructed by your doctor or nurse under the skin (subcutaneously). Injection sites include upper arms, buttocks, upper leg, and abdomen. Do not massage the area of injection after injecting.

To prevent hard lumps from developing at one site, rotate injection sites.

Do not change insulin type or brand unless advised by your doctor, as it may require a dosage modification.

Opened cartridges stay good at room temperature for up to four weeks.

Do not keep this medication in a freezer.

Humalog Mix25 should appear cloudy or milky after mixing well.

Always carry glucose tablets, candy, or a sugary drink if blood sugar levels drop too low.

Side Effects

Other significant side effects include allergic reactions at the site of injection. This can usually include swelling, redness, itching, and lumps (lipodystrophy) at the injection area.

Common side effects with Humalog Mix 25 100IU/ml Cartridge include hypoglycemia, injection site allergic reactions, lipodystrophy (pits or skin thickening at the injection site), itching, rashes, sweating, vomiting, headache, palpitations, and listlessness.

Humlog M25Cartridge-100u/mL

5 cartridges, 10 cartridges, 15 cartridges, 20 cartridges, 25 cartridges


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Humalog Mix 25 Cartridges 100 Units/mL
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