Semaglutide has recently been approved by the United States medicines regulator, the FDA, to aid weight loss. Like the Saxenda weight loss pen it is an injection that can be used to suppress your appetite and therefore aid in your weight loss journey. The only difference between Saxenda and Wegovy is that Saxenda is once-daily dosing and Wegovy is a once-weekly dosing.
What is Wegovy?
Wegovy is a prescription-only weight loss injection. The active ingredient in Wegovy is semaglutide, this is the same drug that is in Ozempic. The difference between Ozempic and Wegovy is that Ozempic is only licensed for use in diabetics and it comes in a different strength compared to Wegovy, which comes in a single strength of 2.4mg.
The Wegovy (semaglutide) injection 2.4 mg is an injectable prescription medicine used for adults with obesity (BMI ≥30) or overweight (excess weight) (BMI ≥27) who also have weight-related medical problems (e.g. high blood pressure, type-2-diabetes, high cholesterol) to help them lose weight and keep the weight off.
- Wegovy should only be used with a reduced calorie meal plan and regular exercise. Wegovy alone will not reduce your weight if taken alone without any other life style adjustments.
- Wegovy™ contains semaglutide, a GLP-1 receptor agonist and should NOT be used in conjunction with other GLP-1 agonists such as Saxenda or Ozempic.
- There is insufficient data regarding whether taking Wegovy™ in conjunction with other prescription, over-the-counter or herbal weight loss products is safe and/or effective.
How Does Wegovy Work?
Wegovy is a self injectable weight loss treatment. It contains the active ingredient semaglutide which is very similar to a naturally occurring hormon in the human body called Glucagon-Like Peptide 1 (GLP-1), which belongs to a family of hormones in the body called incretins.
After a meal GLP-1 is naturally released from your intestines to help regulate your blood sugar levels and reduce the amount of glucagon in your body. Glucagon is a naturally occurring hormone that works by inhibiting the action of insulin. As a result, it makes you feel less hungry, slows down the emptying of your stomach and makes you feel ‘fuller’ for longer.
In summary, Wegovy ‘tricks’ your body into producing more GLP-1 and therefore sends signals to your brain that you are full and do not need to eat.
The most commonly reported side effects in clinical trials were:
- Nausea (reported in 44% of patients)
- Diarrhoea (reported in 30% of patients)
- Vomiting (reported in 24% of patients)
- Constipation (reported in 24% of patients)
Other side effects included abdominal pain, headache, fatigue, and dizziness.
In animal studies, semaglutide was associated with an increased risk of thyroid tumours. This link has not been determined in humans, but Wegovy should not be taken by people with a personal or family history of thyroid tumours or a condition called MEN-2.
Wegovy has been associated with other serious side effects like acute pancreatitis, gallbladder disease, heart rate increase and kidney injury.
0.25mg, 0.5mg, 1mg, 1.7mg, 2.4mg